FrailtyCompRisk - Competing Risks Models for Multi-Center Survival Data with
Frailty
Implements methods for analyzing competing risks data in
multi-center survival studies using frailty models. The
approach relies on a mixed proportional hazards model for the
sub-distribution, allowing for cluster-specific random effects.
The package provides tools for model estimation with or without
frailty using Maximum Likelihood (ML) and Restricted Maximum
Likelihood (REML). It supports flexible modeling of
between-center heterogeneity and is particularly suited for
multi-center clinical trials or registries. Core features
include data simulation, likelihood computation,
cluster-dependent censoring options, and testing of frailty
effects. For methodological details, see Katsahian et al.
(2006) <doi:10.1002/sim.2684>.